Molecular Biology and Genetic Epidemiology
Τranscriptional regulation of gene expression, transcription factors such as nuclear hormone receptors, hypoxia inducible factor (HIF), contribution of genetic polymorphisms to the etiology of multifactorial human diseases, genetic association studies of SNPs with diseases, meta-analysis of genetic association studies, GWAS, microarrays and RNAseq.
Dr Braliou received her University degree in the field of Chemistry from the University of Athens. In May 1995 was accepted as a PhD student in the European Molecular Biology Laboratories (EMBL) in Heidelberg Germany. In November 1996 she moved to University of Nijmegen the Netherlands following her supervisor, Prof Henk Stunnenberg, and received her PhD diploma in the field of Molecular Biology /Biochemistry at January 2001.
The research of Dr Braliou is focused on two main directions. In the first one which covers mostly Molecular Biology and Biochemistry her focus is on transcriptional regulation of gene expression by molecules that exert their action in the nucleus such as nuclear hormone receptors, hypoxia inducible factor or other transcription factors and co-factors, to elucidate mechanisms underlying diseases. In the second field, which covers mostly the area of Genetic Epidemiology her interest is in the contribution of genetic polymorphisms in the aetiology of multifactorial human diseases. With the case-control design applied in genetic association studies, she investigates SNPs implicated in the aetiology of diseases. In the same line, she also uses meta-analysis of genetic-association studies and GWASs in an effort to detect weak genotype-disease associations that most case-control studies do not have the power to detect. Finally, molecular biology techniques can be applied to the variants identified in order to elucidate mechanisms that underlie their action.
Since 2003, she serves in the University of Thessaly as a adjunct assistant professor/lecturer teaching ‘Molecular Basis of Genetic Diseases’, ‘Population Genetics’, ‘Genetic Epidemiology’, ‘Biology’, ‘Biochemistry’ and ‘Clinical Biochemistry’ ‘Molecular Biology and Genetics’ at under- and post-graduate level in the Departments of ‘Biochemistry & Biotechnology’ and of ‘Computer Science & Biomedical Informatics’. Since 2018 she serves as assistant professor of Molecular Biology and Genetic Epidemiology in the department of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.
Until today, her publication record includes:
Dr Braliou speaks English fluently and German and Dutch moderately.