Biochemistry (1ΚB06)
Instructor : Braliou Georgia
Course typeCompulsory
Semester1
TermFall Semester
ECTS4
Teaching hours3
Laboratory hours
Description
Construction, classification and nomenclature of organic compounds. Types of chemical bonds and non-covalent bonds. Isomerism: syntactical isomerism, stereoisomerism (optical isomerism, diastereoisomerism). Aromatic compounds. Introduction to Biochemistry (acid- base concepts, buffers). Protein structure and function (amino acids, peptides, proteins). Enzymes (structure, mechanisms of action, control of enzymatic activities, inhibitors, coenzymes). Structure and function of Nucleic Acids (DNA, RNA). Structure and function of Carbohydrates (monosaccharides, disaccharides, oligosaccharides, polysaccharides). Structure and function of lipids (fatty acids, triacyloglycerols, phospholipids, glycolipids, lipoproteins, steroids). Introduction to biological membranes (structure, receptors). Metabolism of biomolecules (basic concepts and design, ATP). Metabolism of carbohydrates (glycolysis, citric acid cycle, oxidative phosphorylation, pentose phosphate pathway, gluconeogenesis). Fatty acid metabolism (β- oxidation, ketone bodies, biosynthesis of cholesterol). Protein metabolism (decarboxylation, transamination, urea cycle). Hormones (structure, action mechanisms, function).
Course objectives

 The objectives of the course are to familiarize students with:

  • Basic biochemical concepts
  • The structure, function and chemical properties of biomolecules (proteins, carbohydrates, lipids and nucleic acids)
  • Enzyme kinetics
  • Coupled reactions and enzyme-catalyzed reactions of the human body that lead to the essential for survival production of biomolecules, energy and membrane potential
  • The regulation of key metabolic pathways, and how these reflect the energy balance necessary to keep the state of health in man.
Textbooks/Bibliography
  • Τίτλος: ΒΙΟΧΗΜΕΙΑ ΤΟΜΟΣ Ι Συγγραφέας : BERG J.M., TYMOCZKO J.L., STRYER L. Εκδοτικός Οίκος: ΙΤΕ-ΠΑΝΕΠΙΣΤΗΜΙΑΚΕΣ ΕΚΔΟΣΕΙΣ ΚΡΗΤΗΣ Τόπος & Χρόνος Έκδοσης: 2009 ISBN: 978-960-524-190-2 Κωδικός ΕΥΔΟΞΟΣ: 350
  • Τίτλος: Βιοχημεία Συγγραφείς: Karlson Peter Εκδοτικός Οίκος : K. & Ν. ΛΙΤΣΑΣ Ο.Ε. Τόπος & Χρόνος Έκδοσης: Έκδοση: 14η έκδ./1998 ISBN: 96 0-372-013-5 Κωδικός ΕΥΔΟΞΟΣ: 25250
  • Τίτλος: Lehninger Βασικές Αρχές Βιοχημείας Συγγραφείς: Nelson D., Cox M. Εκδοτικός Οίκος : ΕΚΔΟΣΕΙΣ Π.Χ. ΠΑΣΧΑΛΙΔΗΣ Τόπος & Χρόνος Έκδοσης: 1η έκδ./2011 ISBN: 9789604892204 Κωδικός ΕΥΔΟΞΟΣ: 12602324
Assessment method
Written examinations at the end of the semester.
Course material
Lectures in the classroom using multimedia tools (ppt presentations, video, live-stream lectures) Consolidation exercises during the lectures Material in e-class (lectures power-point, suggested exercises) Additional recommended readings